Monozygous twins concordant for duodenojejunal villous atrophy and dermatitis herpetiformis.
نویسندگان
چکیده
A pair of monozygous twins concordant for both duodenojejunal villous atrophy and dermatitis herpetiformis are described, the first example to be reported in the literature. The observation provides strong support for the concept of an underlying genetic component being involved in the pathogenesis of these two conditions.
منابع مشابه
Dermatitis herpetiformis: jejunal findings and skin
Fifty seven children with dermatitis herpetiformis, 18 from Finland and 39 from Hungary, were studied. Diagnostic criteria included the finding of granular IgA deposits in the skin of all patients. The mean age at onset of the rash was 7-2 years and favoured sites were the elbows, knees, and buttocks. Symptoms suggesting small intestinal disease were rare but in 35 (61%) of the children subtota...
متن کاملTreatment of dermatitis herpetiformis with corticosteroids
The jejunal morphological and functional response to either a gluten-free diet or corticosteroid therapy was studied in six patients with dermatitis herpetiformis. In each treatment group there were two patients with subtotal villous atrophy and one with partial villous atrophy. After treatment, in both groups, morphological improvement was seen in villous and surface cell heights, mucosal thic...
متن کاملAmino acid and peptide absorption in patients with coeliac disease.
A double-lumen perfusion technique has been used to study amino acid and peptide absorption in eight normal control subjects, 13 patients with untreated adult coeliac disease, and 16 patients with dermatitis herpetiformis who had varying morphological abnormalities of the small bowel. All subjects were perfused with isotonic solutions containing 10 mM glycyl-L-alanine and 10 mM glycine + 10 mM ...
متن کاملDermatitis herpetiformis: diagnosis, diet and demography.
We describe a long term study of 76 patients with dermatitis herpetiformis. Unlike patients with coeliac disease, where the peak incidence was during the first and fourth decades, no dermatitis herpetiformis patients presented in the first decade; also, there was a male preponderance in dermatitis herpetiformis which contrasts with the excess of females in coeliac disease. The apparent prevalen...
متن کاملDermatitis herpetiformis: jejunal findings and skin response to gluten free diet.
Fifty seven children with dermatitis herpetiformis, 18 from Finland and 39 from Hungary, were studied. Diagnostic criteria included the finding of granular IgA deposits in the skin of all patients. The mean age at onset of the rash was 7 X 2 years and favoured sites were the elbows, knees, and buttocks. Symptoms suggesting small intestinal disease were rare but in 35 (61%) of the children subto...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Gut
دوره 27 8 شماره
صفحات -
تاریخ انتشار 1986